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In Kyphoplasty, a surgical device or instruments are inserted into the broken vertebra to reduce the vertebral body collapse towards its original shape. The hole created after removal of the surgical device or instruments is then filled with stabilizing material. The material is left in place, stabilizing the fracture in the improved vertebral shape.

In Vertebroplasty, the procedure involves either no manipulation or only external reduction of the fracture by extension, i.e., physical manipulation of the patient when placing the patient on the operating table before the material is injected into the fracture site.